relation between the degree of renal functional impairment and haemoglobin A1 in non diabetic patients with chronic renal failure

The study was undertaken to investigate whether there is some correlation of the degree of renal functional impairment [as determined by serum creatinine and creatinine clearance rate] with haemoglobin A1 end stage renal disease. Thirty six nondiabetic patients were selected for the study. Four age groups and three disease groups of the patients were recognized. A weak inverse correlation was observed between the level of serum creatinine and haemoglobin A1 in patients of age group 46 to 65 years [r = - 0.46, p < 0.1]

Characterization of a reptilian aldolase

The optimum pH of fructose-1, 6-diphosphate aldolase from thigh muscles was found to be 9. The pK values of amino acids present at the active centre were found to be 7 and 9.7 corresponding to Imidazolium group of histidine and E1-ammonium group of lysine, respectively. The Km value and Vmax were found to be 63.49 mM and 10 S-L units, respectively